|
KMID : 0366220130480040287
|
|
Korean Journal of Hematology
2013 Volume.48 No. 4 p.287 ~ p.291
|
|
|
Nodular lymphoid hyperplasia of the stomach in a patient with multiple submucosal tumors
|
|
Jeon Ja-Young
Lim Sun-Gyo
Kim Jang-Hee
Lee Kee-Myung
Cho Sung-Ran
Han Jae-Ho
|
|
|
Abstract
|
|
|
|
Nodular lymphoid hyperplasia of the stomach is a rare lymphoproliferative disorder. Here, we report a 38-year-old man who presented with multiple submucosal tumors of the stomach. Histologically, the lesions were characterized by multiple discrete submucosal nodules of lymphoid cells. The infiltrates between the lymphoid follicles were composed mainly of medium-sized lymphoid cells with abundant clear cytoplasm, as well as a few large cells with vesicular nuclei. The gastric mucosa exhibited multifocal lymphoid ag-gregates and some of the epithelial cells were infiltrated by small lymphocytes mimicking lymphoepithelial lesions. Histopathology was consistent with mucosa-associated lym-phoid tissue lymphoma. However, the infiltrating lymphoid cells were positive for CD2, CD3, CD5, and CD7. In addition, polymerase chain reaction analysis of the im-munoglobulin heavy chain and T-cell receptor gene rearrangements demonstrated polyclonality. This case was diagnosed as reactive lymphoid hyperplasia of the stomach.
|
|
|
KEYWORD
|
|
|
Lymphoid hyperplasia, Stomach, MALToma
|
|
|
FullTexts / Linksout information
|
|
  
|
|
|
Listed journal information
|
|
  
|